
Green Tea EGCG Benefit In Cardiovascular Disease Controlling As our community is becoming richer, people are more health sensitive nowadays. In term of drink, green tea is treated as the healthiest drink as it is not only has the rehydrate function, but it is also flavonoid rich that can protect our body from heart attack. Investigation on green tea drinkers show that they are somewhat little vulnerable to a wide range of diseases, from viral infection to chronic degenerative disease like stroke, cancer, heart disease and osteoporosis. Study indicates that green tea has very high level of flavonoids (antioxidant) which consist of catechins and their derivatives. Antioxidant is the biological process that prevents the oxidation which will produce highly reactive free radicals. Flavonoids substance comprises of larger than 1/3 of the green tea dry weight. Epigallocatechin-3-gallate (EGCG) is the largest abundant catechin in all green tea. It has the upmost antioxidant activity of all green tea's catechins and hence is believed to play the most significant role in the green tea's anticancer and antioxidant effect. Green tea EGCG is so rich that a cup of green tea may have 20-35mg of it. In our arteries, there is a one cell thick lining that behaves as the boundary layer between the bloodstream and the wall of the artery where blood plaques can form, this is known as arterial endothelium. When heart disease occurs, a type of enzyme will hasten the production of free radicals in the artery endothelium, thus escalates the level of free radicals in arteries quickly. Green tea EGCG will inhibit the enzymes required in the fabrication of the free radicals and thus protects the endothelium from ruined by free radical. Because of this green tea is playing an important role in preventing cardiovascular disease. EGCG also serves in curbing the death of heart muscle cells after ischemia/reperfusion injury, by stopping the activation of inflammation compounds (STAT-1) that will induce oxidative injury which kills heart cell in reperfusion injury. Moreover, cancer cells need enzyme dihydrofolate reductase (DHFR) to create DNA and multiply. EGCG will interfere with the DHFR and is practically prevents the development of cancer cells. Furthermore, EGCG manage to also speed up the recovery of damaged heart cells, and in this way allowing quick healing of tissues and relieving organs damage. In conclusion, green tea EGCG has outstanding benefit in helping heart disease curbing as well as in heart disease damage recovery. As such for those who are suffering from cardiovascular disease and those who are health sensitive, green tea is the excellent option of beverage for them. 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